MS-SMART recruitment complete

29 June 2016

We are delighted to be able to tell you that we have completed recruiting people to take part in MS-SMART, a clinical trial of three drugs in multiple sclerosis (MS).

MS-SMART is a major UK-wide phase 2 clinical trial that will test whether three existing drugs can slow the progression of disability in people with secondary progressive MS (SPMS) – a late stage and untreatable progressive form of the condition

Researchers will test the safety and effectiveness of amiloride (licensed to treat heart disease), fluoxetine (depression) or riluzole (motor neurone disease) against a dummy drug (placebo) in 440 people with SPMS.

Read more about the trial

We started recruiting people at the Anne Rowling Clinic in Spring 2015.

We have screened and recruited 104 people who met the eligibility criteria and agreed to participate. These people have now been 'randomised', i.e. assigned to receive one of the drugs or a placebo (they do not know which).

The first people we recruited are now coming back for their week 48 visit, at which point they only have another two study visits to go.

Thank you to everyone who is taking part in this important study! We are looking forward to sharing the report when the trial is complete.

Trial website: www.ms-smart.org

For updates, follow the MS-SMART Scotland Twitter feed

 

In the trial researchers will test the safety and effectiveness of amiloride (licensed to treat heart disease), fluoxetine (depression) or riluzole (motor neurone disease) against a dummy drug (placebo) in 440 people with secondary progressive MS – a late stage and untreatable progressive form of the condition. - See more at: http://annerowlingclinic.com/news/launch-of-ms-smart#sthash.EfMEqmHa.dpuf
slow disability progression in people with secondary progressive multiple sclerosis (MS). - See more at: http://annerowlingclinic.com/news/launch-of-ms-smart#sthash.EfMEqmHa.dpuf
slow disability progression in people with secondary progressive multiple sclerosis (MS). - See more at: http://annerowlingclinic.com/news/launch-of-ms-smart#sthash.EfMEqmHa.dpuf

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